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The SLC2 (GLUT) family of membrane transporters

317 , E1121E1130 (2019)

Despite higher body fat content, Ecuadorian subjects with Laron syndrome have less insulin resistance and lower incidence of diabetes than their relatives

Dysregulated adipokines disrupts normal adipokine signaling, promoting oxidative stress through ROS generation and contributing to endothelial dysfunction [152]

This is critical because even "pure" peptides can carry endotoxins that trigger unwanted inflammatory responses in cell cultures or animal models